Multiple Fates of L1 Retrotransposition Intermediates in Cultured Human Cells

LINE-1 (L1) retrotransposons comprise ∼17% of human DNA, yet little is known about L1 integration. Here, we characterized 100 retrotransposition events in HeLa cells and show that distinct DNA repair pathways can resolve L1 cDNA retrotransposition intermediates. L1 cDNA resolution can lead to variou...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gilbert, Nicolas, Lutz, Sheila, Morrish, Tammy A., Moran, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190285/
https://ncbi.nlm.nih.gov/pubmed/16107723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7780-7795.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados