Loss of the Serine/Threonine Kinase Fused Results in Postnatal Growth Defects and Lethality Due to Progressive Hydrocephalus

The Drosophila Fused (Fu) kinase is an integral component of the Hedgehog (Hh) pathway that helps promote Hh-dependent gene transcription. Vertebrate homologues of Fu function in the Hh pathway in vitro, suggesting that Fu is evolutionarily conserved. We have generated fused (stk36) knockout mice to...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Merchant, Mark, Evangelista, Marie, Luoh, Shiuh-Ming, Frantz, Gretchen D., Chalasani, Sreedevi, Carano, Richard A. D., van Hoy, Marjie, Ramirez, Julio, Ogasawara, Annie K., McFarland, Leanne M., Filvaroff, Ellen H., French, Dorothy M., de Sauvage, Frederic J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190232/
https://ncbi.nlm.nih.gov/pubmed/16055717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7054-7068.2005
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы