Male Infertility, Impaired Sperm Motility, and Hydrocephalus in Mice Deficient in Sperm-Associated Antigen 6

Gene targeting was used to create mice lacking sperm-associated antigen 6 (Spag6), the murine orthologue of Chlamydomonas PF16, an axonemal protein containing eight armadillo repeats predicted to be important for flagellar motility and stability of the axoneme central apparatus. Within 8 weeks of bi...

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Detalhes bibliográficos
Main Authors: Sapiro, Rossana, Kostetskii, Igor, Olds-Clarke, Patricia, Gerton, George L., Radice, Glenn L., Strauss III, Jerome F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134010/
https://ncbi.nlm.nih.gov/pubmed/12167721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6298-6305.2002
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