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Nucleotide modulation of the activity of rat heart ATP-sensitive K+ channels in isolated membrane patches.

1. We have measured the ATP dependence of KATP channel activity, and the effect of various metabolites on this relationship, in inside-out membrane patches isolated from rat ventricular myocytes. 2. The inhibition of KATP channel activity by ATP could be described as a sigmoid function of [ATP] with...

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Detalhes bibliográficos
Main Authors: Lederer, W J, Nichols, C G
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190004/
https://ncbi.nlm.nih.gov/pubmed/2621629
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