The Zebrafish Mutants dre, uki, and lep Encode Negative Regulators of the Hedgehog Signaling Pathway

Proliferation is one of the basic processes that control embryogenesis. To identify factors involved in the regulation of proliferation, we performed a zebrafish genetic screen in which we used proliferating cell nuclear antigen (PCNA) expression as a readout. Two mutants, hu418B and hu540A, show in...

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Main Authors: Koudijs, Marco J, den Broeder, Marjo J., Keijser, Astrid, Wienholds, Erno, Houwing, Saskia, van Rooijen, Ellen M. H. C., Geisler, Robert, van Eeden, Fredericus J. M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2005
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189072/
https://ncbi.nlm.nih.gov/pubmed/16121254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010019
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