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Hedgehog signalling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signalling in zebrafish

Multiple signalling pathways control the specification of endothelial cells (ECs) to become arteries or veins during vertebrate embryogenesis. Current models propose that a cascade of Hedgehog (Hh), Vascular Endothelial Growth Factor (VEGF) and Notch signalling acts instructively on ECs to control t...

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Hlavní autoři: Wilkinson, Robert N., Koudijs, Marco J., Patient, Roger K., Ingham, Philip W., Schulte-Merker, Stefan, van Eeden, Fredericus J.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833038/
https://ncbi.nlm.nih.gov/pubmed/22668851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-383729
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