The Zebrafish Mutants dre, uki, and lep Encode Negative Regulators of the Hedgehog Signaling Pathway

Proliferation is one of the basic processes that control embryogenesis. To identify factors involved in the regulation of proliferation, we performed a zebrafish genetic screen in which we used proliferating cell nuclear antigen (PCNA) expression as a readout. Two mutants, hu418B and hu540A, show in...

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Detalhes bibliográficos
Main Authors: Koudijs, Marco J, den Broeder, Marjo J., Keijser, Astrid, Wienholds, Erno, Houwing, Saskia, van Rooijen, Ellen M. H. C., Geisler, Robert, van Eeden, Fredericus J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189072/
https://ncbi.nlm.nih.gov/pubmed/16121254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010019
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