Overexpression of cathepsin K during silica-induced lung fibrosis and control by TGF-β

BACKGROUND: Lung fibrosis is characterized by tissue remodeling resulting from an imbalance between synthesis and degradation of extracellular organic matrices. To examine whether cathepsin(s) (Cat) are important in the development of pulmonary fibrosis, we assessed the expression of four Cat known...

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Bibliografiske detaljer
Main Authors: van den Brûle, Sybille, Misson, Pierre, Bühling, Frank, Lison, Dominique, Huaux, François
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1188077/
https://ncbi.nlm.nih.gov/pubmed/16045809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-84
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