Overexpression of cathepsin K during silica-induced lung fibrosis and control by TGF-β

BACKGROUND: Lung fibrosis is characterized by tissue remodeling resulting from an imbalance between synthesis and degradation of extracellular organic matrices. To examine whether cathepsin(s) (Cat) are important in the development of pulmonary fibrosis, we assessed the expression of four Cat known...

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Bibliographic Details
Main Authors: van den Brûle, Sybille, Misson, Pierre, Bühling, Frank, Lison, Dominique, Huaux, François
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1188077/
https://ncbi.nlm.nih.gov/pubmed/16045809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-84
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