Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy

Currently no definitive biomarker of Alzheimer's disease (AD) is available, and this impedes both clinical diagnosis in humans and drug discovery in transgenic animal models. Proton magnetic resonance spectroscopy ((1)H MRS) provides a noninvasive way to investigate in vivo neurochemical abnorm...

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Autori principali: Marjanska, Malgorzata, Curran, Geoffrey L., Wengenack, Thomas M., Henry, Pierre-Gilles, Bliss, Robin L., Poduslo, Joseph F., Jack, Clifford R., Uğurbil, Kâmil, Garwood, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1188012/
https://ncbi.nlm.nih.gov/pubmed/16091461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505513102
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