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Vitamin C biosynthesis in trypanosomes: A role for the glycosome

The capacity to synthesize vitamin C (ascorbate) is widespread in eukaryotes but is absent from humans. The last step in the biosynthetic pathway involves the conversion of an aldonolactone substrate to ascorbate, a reaction catalyzed by members of an FAD-dependent family of oxidoreductases. Here we...

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Detalhes bibliográficos
Main Authors: Wilkinson, Shane R., Prathalingam, S. Radhika, Taylor, Martin C., Horn, David, Kelly, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187986/
https://ncbi.nlm.nih.gov/pubmed/16087875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504251102
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