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Vitamin C biosynthesis in trypanosomes: A role for the glycosome
The capacity to synthesize vitamin C (ascorbate) is widespread in eukaryotes but is absent from humans. The last step in the biosynthetic pathway involves the conversion of an aldonolactone substrate to ascorbate, a reaction catalyzed by members of an FAD-dependent family of oxidoreductases. Here we...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1187986/ https://ncbi.nlm.nih.gov/pubmed/16087875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504251102 |
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