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Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction

Impaired endothelial nitric oxide synthase (eNOS) function is associated with erectile dysfunction in diabetes mellitus, but the exact molecular basis for the eNOS defect in the diabetic penis remains unclear. We investigated whether hyperglycemia increases O-GlcNAc modification of eNOS in the penis...

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Detalhes bibliográficos
Main Authors: Musicki, Biljana, Kramer, Melissa F., Becker, Robyn E., Burnett, Arthur L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187969/
https://ncbi.nlm.nih.gov/pubmed/16085713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502488102
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