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Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction

Impaired endothelial nitric oxide synthase (eNOS) function is associated with erectile dysfunction in diabetes mellitus, but the exact molecular basis for the eNOS defect in the diabetic penis remains unclear. We investigated whether hyperglycemia increases O-GlcNAc modification of eNOS in the penis...

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Bibliografiske detaljer
Main Authors: Musicki, Biljana, Kramer, Melissa F., Becker, Robyn E., Burnett, Arthur L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187969/
https://ncbi.nlm.nih.gov/pubmed/16085713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502488102
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