The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast

We identified a truncated allele of dam1 as a multicopy suppressor of the sensitivity of cdc13-117 (cyclin B) and mal3-1 (EB-1) cells to thiabendazole, a microtubule poison. We find that Dam1 binds to the plus end of spindle microtubules and kinetochores as cells enter mitosis and this is dependent...

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Main Authors: Sanchez-Perez, Isabel, Renwick, Steven J, Crawley, Karen, Karig, Inga, Buck, Vicky, Meadows, John C, Franco-Sanchez, Alejandro, Fleig, Ursula, Toda, Takashi, Millar, Jonathan B A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187944/
https://ncbi.nlm.nih.gov/pubmed/16079915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600761
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