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Fission Yeast Kinesin-8 Klp5 and Klp6 Are Interdependent for Mitotic Nuclear Retention and Required for Proper Microtubule Dynamics

Fission yeast has two kinesin-8s, Klp5 and Klp6, which associate to form a heterocomplex. Here, we show that Klp5 and Klp6 are mutually dependent on each other for nuclear mitotic localization. During interphase, they are exported to the cytoplasm. In sharp contrast, during mitosis, Klp5 and Klp6 re...

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Detalhes bibliográficos
Main Authors: Unsworth, Amy, Masuda, Hirohisa, Dhut, Susheela, Toda, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592636/
https://ncbi.nlm.nih.gov/pubmed/18799626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0224
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