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Flexibility in substrate recognition by thimet oligopeptidase as revealed by denaturation studies
Thimet oligopeptidase (TOP) is a soluble metalloendopeptidase belonging to a family of enzymes including neurolysin and neprilysin that utilize the HEXXH metal-binding motif. TOP is widely distributed among cell types and is able to cleave a number of structurally unrelated peptides. A recent focus...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Portland Press Ltd.
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186714/ https://ncbi.nlm.nih.gov/pubmed/15647004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041481 |
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