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Flexibility in substrate recognition by thimet oligopeptidase as revealed by denaturation studies
Thimet oligopeptidase (TOP) is a soluble metalloendopeptidase belonging to a family of enzymes including neurolysin and neprilysin that utilize the HEXXH metal-binding motif. TOP is widely distributed among cell types and is able to cleave a number of structurally unrelated peptides. A recent focus...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186714/ https://ncbi.nlm.nih.gov/pubmed/15647004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041481 |
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