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Interferon-γ-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes

IFNγ (interferon-γ) binding to its cognate receptor results, through JAK (Janus kinase), in direct activation of receptor-bound STAT1 (signal transducer and activator of transcription 1), although there is evidence for additional activation of a MAPK (mitogen-activated protein kinase) pathway. In th...

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書誌詳細
主要な著者: Halfter, Ursula M., Derbyshire, Zachary E., Vaillancourt, Richard R.
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186689/
https://ncbi.nlm.nih.gov/pubmed/15601262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041236
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