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The effects of unsaturated fatty acids on hepatic microsomal drug metabolism and cytochrome P-450
1. The effects of unsaturated fatty acids on drug-metabolizing enzymes in vitro were measured by using rat and rabbit hepatic 9000g supernatant fractions. 2. Unsaturated fatty acids inhibited the hepatic microsomal metabolism of `type I' drugs with inhibition increasing with unsaturation: arach...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1969
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1185136/ https://ncbi.nlm.nih.gov/pubmed/4390924 |
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