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The effects of unsaturated fatty acids on hepatic microsomal drug metabolism and cytochrome P-450

1. The effects of unsaturated fatty acids on drug-metabolizing enzymes in vitro were measured by using rat and rabbit hepatic 9000g supernatant fractions. 2. Unsaturated fatty acids inhibited the hepatic microsomal metabolism of `type I' drugs with inhibition increasing with unsaturation: arach...

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Dettagli Bibliografici
Autori principali: Di Augustine, Richard P., Fouts, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1969
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185136/
https://ncbi.nlm.nih.gov/pubmed/4390924
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