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Binding sites of cholinesterases. Alkylation by an aziridinium derivative
1. Alkylation of acetylcholinesterase and butyrylcholinesterase by 2-chloro-N-(chloroethyl)-N-methyl-2-phenylethylamine was observed. This alkylating agent was more potent than related compounds previously described, and less stable (half-life 8·5min. at 23°). 2. Alkylation had effects on hydrolysis...
में बचाया:
| मुख्य लेखक: | |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
1969
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1184755/ https://ncbi.nlm.nih.gov/pubmed/5386194 |
| टैग : |
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