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Binding sites of cholinesterases. Alkylation by an aziridinium derivative
1. Alkylation of acetylcholinesterase and butyrylcholinesterase by 2-chloro-N-(chloroethyl)-N-methyl-2-phenylethylamine was observed. This alkylating agent was more potent than related compounds previously described, and less stable (half-life 8·5min. at 23°). 2. Alkylation had effects on hydrolysis...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1969
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1184755/ https://ncbi.nlm.nih.gov/pubmed/5386194 |
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