Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

Low oxygen levels induce an adaptive response in cells through the activation of HIFs (hypoxia-inducible factors). These transcription factors are mainly regulated by a group of proline hydroxylases that, in the presence of oxygen, target HIF for degradation. The expression of two such enzymes, EGLN...

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Detalhes bibliográficos
Main Authors: Pescador, Nuria, Cuevas, Yolanda, Naranjo, Salvador, Alcaide, Marisa, Villar, Diego, Landázuri, Manuel O., del Peso, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184574/
https://ncbi.nlm.nih.gov/pubmed/15823097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20042121
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