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Negative control of keratinocyte differentiation by Rho/CRIK signaling coupled with up-regulation of KyoT1/2 (FHL1) expression

Rho GTPases integrate control of cell structure and adhesion with downstream signaling events. In keratinocytes, RhoA is activated at early times of differentiation and plays an essential function in establishment of cell–cell adhesion. We report here that, surprisingly, Rho signaling suppresses dow...

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Detalhes bibliográficos
Main Authors: Grossi, Maddalena, Hiou-Feige, Agnès, Di Vignano, Alice Tommasi, Calautti, Enzo, Ostano, Paola, Lee, Sam, Chiorino, Giovanna, Dotto, G. Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183590/
https://ncbi.nlm.nih.gov/pubmed/16061799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505011102
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