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RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2

The DNA-binding protein recombination signal binding protein-Jκ (RBP-J) mediates transcriptional activation of the Notch intracellular domain (NIC). In the absence of transcriptional activators, RBP-J suppresses transcription by recruiting co-suppressors. KyoT2 is a LIM domain protein that inhibits...

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Detalhes bibliográficos
Main Authors: Qin, Hongyan, Wang, Jishu, Liang, Yingmin, Taniguchi, Yoshihito, Tanigaki, Kenji, Han, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC390284/
https://ncbi.nlm.nih.gov/pubmed/14999091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh295
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