The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of α(2)δ subunits is key to trafficking voltage-gated Ca(2)+ channels

All auxiliary α(2)δ subunits of voltage-gated Ca(2+) (Ca(V)) channels contain an extracellular Von Willebrand factor-A (VWA) domain that, in α(2)δ-1 and -2, has a perfect metal-ion-dependent adhesion site (MIDAS). Modeling of the α(2)δ-2 VWA domain shows it to be highly likely to bind a divalent cat...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Cantí, C., Nieto-Rostro, M., Foucault, I., Heblich, F., Wratten, J., Richards, M. W., Hendrich, J., Douglas, L., Page, K. M., Davies, A., Dolphin, A. C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183569/
https://ncbi.nlm.nih.gov/pubmed/16061813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504183102
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares