Generation of Rx(+)/Pax6(+) neural retinal precursors from embryonic stem cells

We report directed differentiaion of retinal precursors in vitro from mouse ES cells. Six3(+) rostral brain progenitors are generated by culturing ES cells under serum-free suspension conditions (SFEB culture) in the presence of Wnt and Nodal antagonists (Dkk1 and LeftyA), and subsequently steered t...

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Bibliographische Detailangaben
Hauptverfasser: Ikeda, Hanako, Osakada, Fumitaka, Watanabe, Kiichi, Mizuseki, Kenji, Haraguchi, Tomoko, Miyoshi, Hiroyuki, Kamiya, Daisuke, Honda, Yoshihito, Sasai, Noriaki, Yoshimura, Nagahisa, Takahashi, Masayo, Sasai, Yoshiki
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183536/
https://ncbi.nlm.nih.gov/pubmed/16076961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500010102
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