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Inhibition of Tat activity by the HEXIM1 protein
BACKGROUND: The positive transcription elongation factor b (P-TEFb) composed by CDK9/CyclinT1 subunits is a dedicated co-factor of HIV transcriptional transactivator Tat protein. Transcription driven by the long terminal repeat (LTR) of HIV involves formation of a quaternary complex between P-TEFb,...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183248/ https://ncbi.nlm.nih.gov/pubmed/15992410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-42 |
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