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Predicting specificity-determining residues in two large eukaryotic transcription factor families
Certain amino acid residues in a protein, when mutated, change the protein's function. We present an improved method of finding these specificity-determining positions that uses all the protein sequence data available for a family of homologous proteins. We study in detail two families of eukar...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183107/ https://ncbi.nlm.nih.gov/pubmed/16085755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki755 |
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