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ERK Phosphorylates p66shcA on Ser36 and Subsequently Regulates p27(kip1) Expression via the Akt-FOXO3a Pathway: Implication of p27(kip1) in Cell Response to Oxidative Stress
Mice deficient for p66shcA represent an animal model to link oxidative stress and aging. p66shcA is implicated in oxidative stress response and mitogenic signaling. Phosphorylation of p66shcA on Ser36 is critical for its function in oxidative stress response. Here we report the identification of ERK...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The American Society for Cell Biology
2005
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1182309/ https://ncbi.nlm.nih.gov/pubmed/15930121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-04-0301 |
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