Assembly of polymorphic genomes: Algorithms and application to Ciona savignyi

Whole-genome assembly is now used routinely to obtain high-quality draft sequence for the genomes of species with low levels of polymorphism. However, genome assembly remains extremely challenging for highly polymorphic species. The difficulty arises because two divergent haplotypes are sequenced to...

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Autors principals: Vinson, Jade P., Jaffe, David B., O'Neill, Keith, Karlsson, Elinor K., Stange-Thomann, Nicole, Anderson, Scott, Mesirov, Jill P., Satoh, Nori, Satou, Yutaka, Nusbaum, Chad, Birren, Bruce, Galagan, James E., Lander, Eric S.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
Matèries:
Methods
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182225/
https://ncbi.nlm.nih.gov/pubmed/16077012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3722605
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