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Assembly of polymorphic genomes: Algorithms and application to Ciona savignyi
Whole-genome assembly is now used routinely to obtain high-quality draft sequence for the genomes of species with low levels of polymorphism. However, genome assembly remains extremely challenging for highly polymorphic species. The difficulty arises because two divergent haplotypes are sequenced to...
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Main Authors: | , , , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Cold Spring Harbor Laboratory Press
2005
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1182225/ https://ncbi.nlm.nih.gov/pubmed/16077012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3722605 |
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