Polyethylene Glycol-Conjugated Adenosine Deaminase (ADA) Therapy Provides Temporary Immune Reconstitution to a Child with Delayed-Onset ADA Deficiency

We describe the effects of polyethylene glycol-conjugated adenosine deaminase (ADA) replacement therapy on lymphocyte counts, activation, apoptosis, proliferation, and cytokine secretion in a 14-month-old girl with “delayed-onset” ADA deficiency and marked immunodysregulation. Pretreatment lymphopen...

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Detalhes bibliográficos
Main Authors: Lainka, Elke, Hershfield, Michael S., Santisteban, Ines, Bali, Pawan, Seibt, Annette, Neubert, Jennifer, Friedrich, Wilhelm, Niehues, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Cellular Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182205/
https://ncbi.nlm.nih.gov/pubmed/16002636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.12.7.861-866.2005
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