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IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency.

Polyethylene glycol (PEG)-modified bovine adenosine deaminase (ADA) is used for replacement therapy of severe combined immunodeficiency disease due to inherited ADA deficiency. We monitored IgG anti-ADA antibody in 17 patients treated by intramuscular injections of PEG-ADA for 1 to greater than 5.5...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Chaffee, S, Mary, A, Stiehm, E R, Girault, D, Fischer, A, Hershfield, M S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443041/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569204/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115761
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