IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency.

Polyethylene glycol (PEG)-modified bovine adenosine deaminase (ADA) is used for replacement therapy of severe combined immunodeficiency disease due to inherited ADA deficiency. We monitored IgG anti-ADA antibody in 17 patients treated by intramuscular injections of PEG-ADA for 1 to greater than 5.5...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Chaffee, S, Mary, A, Stiehm, E R, Girault, D, Fischer, A, Hershfield, M S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569204/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115761
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