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Little Loss of Information Due to Unknown Phase for Fine-Scale Linkage-Disequilibrium Mapping with Single-Nucleotide–Polymorphism Genotype Data

We present the results of a simulation study that indicate that true haplotypes at multiple, tightly linked loci often provide little extra information for linkage-disequilibrium fine mapping, compared with the information provided by corresponding genotypes, provided that an appropriate statistical...

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Hlavní autoři: Morris, A. P., Whittaker, J. C., Balding, D. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181987/
https://ncbi.nlm.nih.gov/pubmed/15077198
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