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Genotype determination for polymorphisms in linkage disequilibrium

BACKGROUND: Genome-wide association studies with single nucleotide polymorphisms (SNPs) show great promise to identify genetic determinants of complex human traits. In current analyses, genotype calling and imputation of missing genotypes are usually considered as two separated tasks. The genotypes...

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Detalhes bibliográficos
Main Authors: Yu, Zhaoxia, Garner, Chad, Ziogas, Argyrios, Anton-Culver, Hoda, Schaid, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753842/
https://ncbi.nlm.nih.gov/pubmed/19228433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-63
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