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Polymorphisms in the Low-Density Lipoprotein Receptor–Related Protein 5 (LRP5) Gene Are Associated with Variation in Vertebral Bone Mass, Vertebral Bone Size, and Stature in Whites

Stature, bone size, and bone mass are interrelated traits with high heritability, but the major genes that govern these phenotypes remain unknown. Independent genomewide quantitative-trait locus studies have suggested a locus for bone-mineral density and stature at chromosome 11q12-13, a region harb...

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Detalhes bibliográficos
Main Authors: Ferrari, Serge L., Deutsch, Samuel, Choudhury, Urmila, Chevalley, Thierry, Bonjour, Jean-Philippe, Dermitzakis, Emmanouil T., Rizzoli, René, Antonarakis, Stylianos E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181981/
https://ncbi.nlm.nih.gov/pubmed/15077203
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