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Selecting a Maximally Informative Set of Single-Nucleotide Polymorphisms for Association Analyses Using Linkage Disequilibrium

Common genetic polymorphisms may explain a portion of the heritable risk for common diseases. Within candidate genes, the number of common polymorphisms is finite, but direct assay of all existing common polymorphism is inefficient, because genotypes at many of these sites are strongly correlated. T...

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Bibliografiske detaljer
Main Authors: Carlson, Christopher S., Eberle, Michael A., Rieder, Mark J., Yi, Qian, Kruglyak, Leonid, Nickerson, Deborah A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181897/
https://ncbi.nlm.nih.gov/pubmed/14681826
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