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How are model protein structures distributed in sequence space?

The figure-to-structure maps for all uniquely folding sequences of short hydrophobic polar (HP) model proteins on a square lattice is analyzed to investigate aspects considered relevant to evolution. By ranking structures by their frequencies, few very frequent and many rare structures are found. Th...

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Detalhes bibliográficos
Autor principal: Bornberg-Bauer, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181141/
https://ncbi.nlm.nih.gov/pubmed/9370433
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