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Radiation-induced cell death: importance of lysosomal destabilization

The mechanisms involved in radiation-induced cellular injury and death remain incompletely understood. In addition to the direct formation of highly reactive hydroxyl radicals (HO(·)) by radiolysis of water, oxidative stress events in the cytoplasm due to formation of H(2)O(2) may also be important....

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Detalhes bibliográficos
Main Authors: Persson, H. Lennart, Kurz, Tino, Eaton, John W., Brunk, Ulf T.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180739/
https://ncbi.nlm.nih.gov/pubmed/15813701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050271
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