Loss of CpG Methylation Is Strongly Correlated with Loss of Histone H3 Lysine 9 Methylation at DMR-LIT1 in Patients with Beckwith-Wiedemann Syndrome

To clarify the chromatin-based imprinting mechanism of the p57(KIP2)/LIT1 subdomain at chromosome 11p15.5 and the mouse ortholog at chromosome 7F5, we investigated the histone-modification status at a differentially CpG methylated region of Lit1/LIT1 (DMR-Lit1/LIT1), which is an imprinting control r...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Higashimoto, Ken, Urano, Takeshi, Sugiura, Kazumitsu, Yatsuki, Hitomi, Joh, Keiichiro, Zhao, Wei, Iwakawa, Mayumi, Ohashi, Hirofumi, Oshimura, Mitsuo, Niikawa, Norio, Mukai, Tsunehiro, Soejima, Hidenobu
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society of Human Genetics 2003
Materias:
Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180615/
https://ncbi.nlm.nih.gov/pubmed/12949703
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares