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Pooled Analysis of Loss of Heterozygosity in Breast Cancer: a Genome Scan Provides Comparative Evidence for Multiple Tumor Suppressors and Identifies Novel Candidate Regions

Somatic loss of heterozygosity (LOH) has been widely reported in breast cancer as a means of identifying putative tumor-suppressor genes. However, individual studies have rarely spanned more than a single chromosome, and the varying criteria used to declare LOH complicate efforts to formally differe...

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Autors principals: Miller, Brian J., Wang, Daolong, Krahe, Ralf, Wright, Fred A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180599/
https://ncbi.nlm.nih.gov/pubmed/13680524
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