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A new direction for gene therapy: intrathymic T cell–specific lentiviral gene transfer
Reports of neoplasia related to insertional activation of protooncogenes by retroviral vectors have raised serious safety concerns in the field of gene therapy. Modification of current approaches is urgently required to minimize the deleterious consequences of insertional mutagenesis. In this issue...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180563/ https://ncbi.nlm.nih.gov/pubmed/16075048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26041 |
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