A carregar...
Mutations of von Hippel-Lindau Tumor-Suppressor Gene and Congenital Polycythemia
The von Hippel-Lindau (pVHL) protein plays an important role in hypoxia sensing. It binds to the hydroxylated hypoxia-inducible factor 1α (HIF-1α) and serves as a recognition component of an E3-ubiquitin ligase complex. In hypoxia or secondary to a mutated VHL gene, the nondegraded HIF-1α forms a he...
Na minha lista:
Main Authors: | , , , , , , , |
---|---|
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society of Human Genetics
2003
|
Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180379/ https://ncbi.nlm.nih.gov/pubmed/12844285 |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|