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Two-Locus Heterogeneity Cannot Be Distinguished from Two-Locus Epistasis on the Basis of Affected-Sib-Pair Data
The observation of multiple linkage signals in the course of conducting genome screens for complex disorders raises the question of whether distinct genes represent independent causes of disease (heterogeneity) or whether they interact to produce the phenotype of interest (epistasis); and there has...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society of Human Genetics
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180363/ https://ncbi.nlm.nih.gov/pubmed/12830401 |
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