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Some epistatic two-locus models of disease. I. Relative risks and identity-by-descent distributions in affected sib pairs
A two-locus disease model is presented in which a marker locus interacts epistatically with another unlinked trait to cause the disease. Such a model can lead to disease-marker associations and distortions in the sharing of marker types among affected family members. These effects are quantified. In...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1981
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1685026/ https://ncbi.nlm.nih.gov/pubmed/6941695 |
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