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A Novel NOD2/CARD15 Haplotype Conferring Risk for Crohn Disease in Ashkenazi Jews

Crohn disease (CD) exhibits a 2–4-fold increased frequency in Jews as compared with other ethnic/racial groups. Three coding variants of the NOD2/CARD15 have been reported as independent disease-predisposing mutations (DPMs), but these were found in only 30%–40% of patients with CD and could not acc...

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Detalhes bibliográficos
Main Authors: Sugimura, Kazuhito, Taylor, Kent D., Lin, Ying-chao, Hang, Tieu, Wang, Dai, Tang, Yong-Ming, Fischel-Ghodsian, Nathan, Targan, Stephan R., Rotter, Jerome I., Yang, Huiying
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180227/
https://ncbi.nlm.nih.gov/pubmed/12577202
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