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Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung

Preterm neonates with respiratory distress syndrome (RDS) often develop a chronic form of lung disease called bronchopulmonary dysplasia (BPD), characterized by decreased alveolar and vascular development. Ventilator treatment with supraphysiological O(2) concentrations (hyperoxia) contribute to the...

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Detalhes bibliográficos
Main Authors: Asikainen, Tiina M., Schneider, Barbara K., Waleh, Nahid S., Clyman, Ronald I., Ho, Wen-Bin, Flippin, Lee A., Günzler, Volkmar, White, Carl W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177409/
https://ncbi.nlm.nih.gov/pubmed/16009933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504520102
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