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Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges

BACKGROUND: Trials in macaque models play an essential role in the evaluation of biomedical interventions that aim to prevent HIV infection, such as vaccines, microbicides, and systemic chemoprophylaxis. These trials are usually conducted with very high virus challenge doses that result in infection...

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Detalhes bibliográficos
Main Authors: Regoes, Roland R, Longini, Ira M, Feinberg, Mark B, Staprans, Silvija I
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176242/
https://ncbi.nlm.nih.gov/pubmed/16018721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020249
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