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Preclinical assessment of HIV vaccines and microbicides by repeated low-dose virus challenges.
BACKGROUND: Trials in macaque models play an essential role in the evaluation of biomedical interventions that aim to prevent HIV infection, such as vaccines, microbicides, and systemic chemoprophylaxis. These trials are usually conducted with very high virus challenge doses that result in infection...
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| Formato: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2005-08-01
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| coleção: | PLoS Medicine |
| Acesso em linha: | http://dx.doi.org/10.1371/journal.pmed.0020249 |
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