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Power to Detect HIV Vaccine Effects in Repeated Low-Dose Challenge Experiments

Simulation studies were conducted to estimate the statistical power of repeated low-dose challenge experiments in non-human primates to detect a candidate HIV vaccine’s effect. The effect of various design parameters on power was explored. Simulation results indicate repeated low-dose challenge stud...

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Auteurs principaux: Hudgens, Michael G., Gilbert, Peter B., Mascola, John R., Wu, Chih-Da, Barouch, Dan H., Self, Steven G.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754821/
https://ncbi.nlm.nih.gov/pubmed/19591571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/600891
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