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Extracellular Signal-regulated Kinase Phosphorylates Tumor Necrosis Factor α-converting Enzyme at Threonine 735: A Potential Role in Regulated Shedding

The ectodomain of certain transmembrane proteins can be released by the action of cell surface proteases, termed secretases. Here we have investigated how mitogen-activated protein kinases (MAPKs) control the shedding of membrane proteins. We show that extracellular signal-regulated kinase (Erk) act...

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Autores principales: Díaz-Rodríguez, Elena, Montero, Juan Carlos, Esparís-Ogando, Azucena, Yuste, Laura, Pandiella, Atanasio
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC117622/
https://ncbi.nlm.nih.gov/pubmed/12058067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-11-0561
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