Down-Regulation of Protease-activated Receptor-1 Is Regulated by Sorting Nexin 1
Degradation or “down-regulation” of protease-activated receptor-1 (PAR1), a G protein-coupled receptor for thrombin, is critical for termination of receptor signaling. Toward understanding the molecular mechanisms by which activated PAR1 is internalized, sorted to lysosomes, and degraded, we investi...
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| Publicado no: | Mol Biol Cell |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Cell Biology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117618/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12058063/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E01-11-0131 |
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